Anti-SIRT1 Monoclonal Antibody

英文名称	Anti-SIRT1 Monoclonal Antibody
宿主	Mouse
别名	SIR2;SIR2alpha;SIR2L1;SIR2-like protein 1;Hsir2
应用	WB IP
稀释比例	WB 1:1000.
交叉反应	Human
蛋白分子量	61/82kDa
Gene ID	23411
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG2b
免疫原	Purified recombinant human SIRT1 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human SIRT1 protein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Mitochondrion Nucleus Nucleus PML body
Swiss Prot	Q96EB6
克隆号	2G10-F4-D9
克隆类型	Monoclonal Antibody
背景资料	This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.The functions of human sirtuins have not yet been determined;however,yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family.Alternative splicing results in multiple transcript variants.[provided by RefSeq,Dec 2008]